Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242653 | 0.82 | KMT2A (0.74) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10522426 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7368692 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8300956 | 0.78 | HSPB1 (0.43) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27439479 | 0.77 | L3MBTL1 (0.51) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5256557 | 0.76 | KMT2A (0.39) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL8099661 | 0.76 | MEN1 (0.66) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| Acetic Acid SCHEMBL4766215 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| Acetic Acid SCHEMBL4766209 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL25309429 | 0.75 | KMT2A (0.65) | ALDH1A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122800-A | Pyrimidinyl acrylic acid derivatives | SANDOZ LTD (CH) | 1996-05-22 | — | — | CN | disclosed |