Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27642279 | 0.94 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EGAACYP1A2 | |
| SCHEMBL27754807 | 0.87 | TSHR (0.42) | ALDH1A1LMNAKDM4EGAAHSD17B10 | |
| SCHEMBL27735019 | 0.82 | PKM (0.45) | ALDH1A1LMNAKDM4EGAAHSD17B10 | |
| SCHEMBL27788104 | 0.82 | CHRM2 (0.50) | KDM4ETDP1CYP2D6CYP2C19KCNH2 | |
| SCHEMBL28794657 | 0.79 | TSHR (0.33) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL27719684 | 0.79 | TSHR (0.40) | ALDH1A1LMNAKDM4EGAAHSD17B10 | |
| SCHEMBL27746996 | 0.78 | LMNA (0.40) | ALDH1A1LMNAGAACYP2C19HPGD | |
| SCHEMBL27448397 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAKDM4EGAAHSD17B10 | |
| SCHEMBL27693671 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAGAAHSD17B10TDP1 | |
| SCHEMBL28815157 | 0.75 | CA1 (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114506-A | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 1996-01-03 | — | — | CN | disclosed |