Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448396 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TDP1NPSR1HTR6 | |
| SCHEMBL27754807 | 0.75 | TSHR (0.42) | ALDH1A1HSD17B10LMNAGAAMAPT | |
| SCHEMBL27642279 | 0.71 | ALDH1A1 (0.41) | ALDH1A1NPSR1LMNAGAAKDM4E | |
| SCHEMBL10904787 | 0.71 | KMT2A (0.46) | ALDH1A1HTR6LMNATSHRPKM | |
| SCHEMBL6526333 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1NPSR1HTR6 | |
| SCHEMBL11246742 | 0.70 | HTR6 (0.41) | ALDH1A1HSD17B10TDP1HTR6LMNA | |
| SCHEMBL27788104 | 0.69 | CHRM2 (0.50) | TDP1HTR6KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL27735019 | 0.69 | PKM (0.45) | ALDH1A1HSD17B10LMNAGAAKDM4E | |
| SCHEMBL5720480 | 0.66 | HTR6 (0.41) | ALDH1A1HSD17B10TDP1NPSR1HTR6 | |
| SCHEMBL10445712 | 0.66 | TSHR (0.43) | ALDH1A1HSD17B10TDP1NPSR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114506-A | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 1996-01-03 | — | — | CN | disclosed |