Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.37 |
| ▸ | CTSC | P53634 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27504186 | 0.91 | TRHR (0.41) | TRHRHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1370995 | 0.88 | TRHR (0.41) | TRHRCTSCHDAC3HDAC1HDAC2 | |
| SCHEMBL27772272 | 0.84 | KLK7 (0.35) | TRHRCTSCGHSRDPP7 | |
| SCHEMBL18048894 | 0.82 | CTSC (0.45) | TRHRCTSCDPP7 | |
| SCHEMBL18048893 | 0.82 | CTSC (0.45) | TRHRCTSCDPP7 | |
| SCHEMBL18104612 | 0.81 | CTSC (0.42) | TRHRCTSCDPP7 | |
| SCHEMBL27639586 | 0.81 | TRHR (0.49) | TRHR | |
| SCHEMBL27448784 | 0.81 | TRHR (0.49) | TRHR | |
| SCHEMBL34467291 | 0.80 | CTSC (0.40) | CTSCGHSRDPP7 | |
| SCHEMBL7649422 | 0.80 | TRHR (0.43) | TRHRHDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101150992-A | Microprojections with capillary control features and method | ALZA CORP (US) | 2008-03-26 | — | — | CN | claimed |
| CN-101137333-A | Solubility-controlling formulations for coated microprojections | ALZA CORP (US) | 2008-03-05 | — | — | CN | claimed |
| CN-1946452-A | Frequency assisted transdermal agent delivery method and system | ALZA CORP (US) | 2007-04-11 | — | — | CN | claimed |
| CN-1863572-A | Method and device for enhancing transdermal agent flux | JOHNSON & JOHNSON (US) | 2006-11-15 | — | — | CN | claimed |
| CN-1863571-A | Method and apparatus for enhancing transdermal flux of pharmaceutical agents | JOHNSON & JOHNSON (US) | 2006-11-15 | — | — | CN | claimed |
| CN-1842320-A | Formulations for coated microprojections containing non-volatile counterions | ALZA CORP (US) | 2006-10-04 | — | — | CN | claimed |
| CN-1842300-A | Method of coating skin piercing microprojections | ALZA CORP (US) | 2006-10-04 | — | — | CN | claimed |
| CN-105722530-A | Designed peptides for tight junction barrier modulation | 罗切斯特大学 | 2016-06-29 | — | — | CN | disclosed |
| CN-1842320-B | Formulations for coated microprojections containing non-volatile counterions | ALZA CORP | 2013-06-19 | — | — | CN | disclosed |
| CN-100591293-C | Microprojections with capillary control features and method | ALZA CORP | 2010-02-24 | — | — | CN | disclosed |
| CN-100586385-C | Transdermal delivery device and method of forming the same | ALZA CORP | 2010-02-03 | — | — | CN | disclosed |
| CN-100571643-C | The self-driven applicator that is used for microprotrusion array | ALZA CORP (US) | 2009-12-23 | — | — | CN | disclosed |
| CN-101252967-A | Method and device for coating a continuous strip of microprojection members | ALZA CORP (US) | 2008-08-27 | — | — | CN | disclosed |
| CN-1897898-A | Pretreatment method and system for enhancing transdermal drug delivery | ALZA CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1863572-A | Method and device for enhancing transdermal agent flux | JOHNSON & JOHNSON (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1863571-A | Method and apparatus for enhancing transdermal flux of pharmaceutical agents | JOHNSON & JOHNSON (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1842320-A | Formulations for coated microprojections containing non-volatile counterions | ALZA CORP (US) | 2006-10-04 | — | — | CN | disclosed |
| CN-1842300-A | Method of coating skin piercing microprojections | ALZA CORP (US) | 2006-10-04 | — | — | CN | disclosed |
| CN-1133472-C | Device for increasing transdermal agent flux | — | 2004-01-07 | — | — | CN | disclosed |
| CN-1233967-A | Device and method for increasing transdermal agent flux | ALZA CORP (US) | 1999-11-03 | — | — | CN | disclosed |