Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 8/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.54 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452500 | 0.93 | KCNK2 (0.59) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL27452652 | 0.86 | TP53 (0.57) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL2243918 | 0.85 | FAAH (0.69) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL7107437 | 0.83 | FAAH (0.67) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL29636830 | 0.82 | RAB9A (0.74) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL7105704 | 0.82 | RAB9A (0.74) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL27452647 | 0.80 | FAAH (0.58) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL20379246 | 0.76 | MMP2 (0.78) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL27452587 | 0.76 | FAAH (0.58) | TP53MMP2MMP9MMP8MMP13 | |
| SCHEMBL10709034 | 0.76 | MGLL (0.70) | TP53MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |