Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 5/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.62 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.62 |
| ▸ | GPR183 | P32249 | 1/20 | 0.62 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.62 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | TACR2 | P21452 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676766 | 1.00 | TNNC1 (0.62) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL6861222 | 0.86 | ESR1 (0.62) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL8028839 | 0.84 | ESR1 (0.64) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL27833284 | 0.84 | ESR1 (0.64) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL8812120 | 0.84 | ESR1 (0.64) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL7900686 | 0.83 | SMN1; SMN2 (0.60) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL351935 | 0.83 | THRA (0.65) | THRATHRBALDH1A1RARBMEN1 | |
| SCHEMBL15655566 | 0.83 | SMN1; SMN2 (0.60) | TNNC1S1PR1SGPL1S1PR4GPR183 | |
| SCHEMBL6835676 | 0.83 | THRA (0.65) | THRATHRBALDH1A1RARBMEN1 | |
| SCHEMBL13617729 | 0.83 | THRA (0.65) | THRATHRBALDH1A1RARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101843897-B | Sphingosine-1-phosphate receptor agonists in the treatment of demyelinating disorders | NOVARTIS AG | 2014-04-30 | — | — | CN | claimed |
| CN-103550195-A | S1p receptor modulators for treating multiple sclerosis | NOVARTIS AG | 2014-02-05 | — | — | CN | claimed |
| CN-103476400-A | Formulations comprising 2-amino-2-[2-(4 - octylphenyl) ethyl] propane -1, 3-diol | NOVARTIS AG | 2013-12-25 | — | — | CN | claimed |
| CN-101791406-B | Use of sphingosine-1-phosphate (S1P) receptor agonists for the treatment of brain degenerative diseases | NOVARTIS AG | 2013-08-14 | — | — | CN | claimed |
| CN-101305990-B | Use of EDG receptor binding agents in cancer | NOVARTIS AG | 2013-06-19 | — | — | CN | claimed |
| CN-101797241-B | Solid pharmaceutical compositions comprising a sip receptor agonist and a sugar alcohol | NOVARTIS AG | 2013-03-27 | — | — | CN | claimed |
| CN-102579387-A | Pharmaceutical compositions comprising an S1P modulator | NOVARTIS AG | 2012-07-18 | — | — | CN | claimed |
| CN-1993115-B | Compound formulations of 2-amino-1, 3-propanediol compounds | NOVARTIS AG (CH) | 2011-12-28 | — | — | CN | claimed |
| CN-102076335-A | Pediatric composition for the treatment of multiple sclerosis | NOVARTIS AG | 2011-05-25 | — | — | CN | claimed |
| CN-101237852-B | Liquid formulations | NOVARTIS AG | 2011-01-26 | — | — | CN | claimed |
| CN-101272780-A | DPP IV inhibitor for use in the treatment of autoimmune diseases and graft rejection | NOVARTIS AG (CH) | 2008-09-24 | — | — | CN | claimed |
| CN-101242829-A | Pharmaceutical composition comprising PPAR regulator | SANKYO CO (JP) | 2008-08-13 | — | — | CN | claimed |
| CN-101132784-A | Ophthalmic use of S1P receptor modulators | NOVARTIS AG (CH) | 2008-02-27 | — | — | CN | claimed |
| CN-101027048-A | Medicinal composition as immunosuppressant | SANKYO CO (JP) | 2007-08-29 | — | — | CN | claimed |
| CN-1708293-A | Sphingosine-1-phosphate receptor agonists for the treatment of demyelinating diseases | NOVARTIS AG (CH) | 2005-12-14 | — | — | CN | claimed |
| CN-1191062-C | Medicinal compsns. | MITSUBISHI PHARMACEUTICAL IND (JP) | 2005-03-02 | — | — | CN | claimed |
| CN-1492757-A | Use of accelerated lymphocyte homing agents for manufacture of medicament for treating delayed graft function in tissue transplant | ��˹��ŵ�� | 2004-04-28 | — | — | CN | claimed |
| CN-1146411-C | New use of 1, 3-propanediol derivatives | ��˹��ŵ�� | 2004-04-21 | — | — | CN | claimed |
| CN-1294511-A | Pharmaceutical composition | YOSHITOMI PHARMACEUTICAL (JP) | 2001-05-09 | — | — | CN | claimed |
| CN-1237906-A | New use of 1, 3-propanediol derivatives | NOVARTIS AG (CH) | 1999-12-08 | — | — | CN | claimed |