Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779015 | 0.87 | POLB (0.40) | OPRK1OPRM1OPRD1HDAC1 | |
| SCHEMBL29027647 | 0.79 | OPRM1 (0.56) | OPRK1OPRM1OPRD1DRD3DRD2 | |
| SCHEMBL154270 | 0.72 | ALDH1A1 (0.48) | OPRM1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL7877735 | 0.72 | ALDH1A1 (0.48) | OPRK1OPRM1OPRD1HDAC1KDM4E | |
| SCHEMBL16653971 | 0.72 | OPRK1 (0.45) | OPRK1OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL8987565 | 0.71 | KCNH2 (0.46) | KCNH2 | |
| Hydrochloric Acid SCHEMBL11203276 | 0.71 | ALDH1A1 (0.47) | OPRK1OPRM1OPRD1DRD3CHRM2 | |
| SCHEMBL6007954 | 0.70 | CA12 (0.46) | OPRK1OPRM1OPRD1DRD3DRD2 | |
| SCHEMBL7125488 | 0.70 | OPRK1 (0.42) | OPRK1OPRM1OPRD1DRD3DRD2 | |
| SCHEMBL26985820 | 0.70 | SIGMAR1 (0.62) | SLC6A2SLC6A4SLC6A3SIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148378-C | 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics | �Ҵ���˾ | 2004-05-05 | — | — | CN | disclosed |
| CN-1119191-A | 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics | FOURNIER IND & SANTE (FR) | 1996-03-27 | — | — | CN | disclosed |