Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463102 | 0.87 | OPRK1 (0.49) | HDAC1OPRM1OPRD1OPRK1 | |
| SCHEMBL7877735 | 0.86 | ALDH1A1 (0.48) | POLBGAABCHEALDH1A1HDAC3 | |
| SCHEMBL16653971 | 0.86 | OPRK1 (0.45) | POLBALDH1A1RORCOPRM1OPRD1 | |
| SCHEMBL10962715 | 0.83 | POLB (0.47) | POLBGAABCHEALDH1A1HDAC3 | |
| SCHEMBL154270 | 0.83 | ALDH1A1 (0.48) | POLBGAABCHEALDH1A1HDAC3 | |
| SCHEMBL17508109 | 0.81 | ALDH1A1 (0.47) | POLBGAABCHEALDH1A1HDAC3 | |
| Hydrochloric Acid SCHEMBL11203276 | 0.81 | ALDH1A1 (0.47) | POLBGAABCHEALDH1A1HDAC3 | |
| SCHEMBL154265 | 0.80 | KCNH2 (0.51) | BCHEMAOBACHEOPRM1 | |
| SCHEMBL2228449 | 0.80 | HTT (0.49) | POLBGAAALDH1A1ACHEOPRM1 | |
| SCHEMBL8398911 | 0.80 | MBTD1 (0.40) | POLBBCHEALDH1A1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669316-B1 | Analogs of 15-deoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER IND & SANTE (FR) | 1997-07-30 | — | — | EP | disclosed |
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |
| EP-0669316-A1 | Analogs of 15-déoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER INDUSTRIE ET SANTE (FR) | 1995-08-30 | — | — | EP | disclosed |