Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 5/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554973 | 0.92 | APP (0.39) | CTNNB1TCF7L2APPMCHR1MEN1 | |
| SCHEMBL6653145 | 0.91 | CTNNB1 (0.36) | CTNNB1TCF7L2APPMCHR1MEN1 | |
| SCHEMBL7654278 | 0.82 | MEN1 (0.42) | CTNNB1TCF7L2APPMEN1KMT2A | |
| SCHEMBL27464342 | 0.80 | SMN1; SMN2 (0.41) | CTNNB1TCF7L2APPMCHR1MEN1 | |
| SCHEMBL7553839 | 0.77 | APP (0.49) | APPKMT2ALMNATP53MAPT | |
| SCHEMBL6651230 | 0.75 | APP (0.47) | APPMEN1KMT2ALMNATP53 | |
| SCHEMBL27463941 | 0.72 | APP (0.46) | APPKMT2ALMNATP53MAPT | |
| SCHEMBL6655631 | 0.72 | APP (0.44) | APPKMT2ALMNATP53MAPT | |
| SCHEMBL27479858 | 0.71 | HSD17B10 (0.44) | KMT2AELANETP53MAPTPOLB | |
| SCHEMBL28054684 | 0.71 | KDM4E (0.47) | APPMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158299-C | 4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, method fo r producing the same, medicaments containing these compounds and their use | ���ĵ�˹ҩ��¹�����˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1374968-A | 4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, method fo r producing the same, medicaments containing these compounds and their use | AVENTIS PHARMA PEUTSCHLAND GMB (DE) | 2002-10-16 | — | — | CN | disclosed |