Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554973 | 0.91 | APP (0.39) | CTNNB1TCF7L2ELANECTRB1APP | |
| SCHEMBL27464341 | 0.91 | CTNNB1 (0.37) | CTNNB1TCF7L2ELANECTRB1APP | |
| SCHEMBL6651230 | 0.85 | APP (0.47) | APPPOLBMEN1KMT2ALMNA | |
| SCHEMBL7654278 | 0.83 | MEN1 (0.42) | CTNNB1TCF7L2APPPOLBMEN1 | |
| SCHEMBL27464342 | 0.79 | SMN1; SMN2 (0.41) | CTNNB1TCF7L2APPPOLBMCHR1 | |
| SCHEMBL6653990 | 0.78 | LMNA (0.45) | LMNAMAPTRXFP1GAA | |
| SCHEMBL6655631 | 0.78 | APP (0.44) | APPPOLBKMT2ALMNATP53 | |
| SCHEMBL6653650 | 0.77 | KMT2A (0.54) | APPPOLBMEN1KMT2A | |
| SCHEMBL7553839 | 0.76 | APP (0.49) | APPPOLBKMT2ALMNATP53 | |
| SCHEMBL6650935 | 0.74 | ACHE (0.42) | ELANECTRB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218401-B1 | 4-BENZYLAMINOQUINOLINE CONJUGATES WITH BILE ACID AND THEIR HETEROANALOGUES, METHODS FOR PRODUCING THE SAME, MEDICAMENTS CONTAINING THESE COMPOUNDS AND THEIR USE | AVENTIS PHARMA GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| EP-1218401-A1 | 4-BENZYLAMINOQUINOLINE CONJUGATES WITH BILE ACID AND THEIR HETEROANALOGUES, METHODS FOR PRODUCING THE SAME, MEDICAMENTS CONTAINING THESE COMPOUNDS AND THEIR USE | Aventis Pharma Deutschland GmbH (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021642-A1 | 4-BENZYLAMINOQUINOLINE CONJUGATES WITH BILE ACID AND THEIR HETEROANALOGUES, METHODS FOR PRODUCING THE SAME, MEDICAMENTS CONTAINING THESE COMPOUNDS AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-03-29 | — | — | WO | disclosed |