Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554973 | 0.82 | APP (0.39) | APPPOLBCTNNB1TCF7L2L3MBTL1 | |
| SCHEMBL7654278 | 0.80 | MEN1 (0.42) | SMN1; SMN2APPPOLBCTNNB1TCF7L2 | |
| SCHEMBL27464341 | 0.80 | CTNNB1 (0.37) | APPPOLBCTNNB1TCF7L2NPC1 | |
| SCHEMBL6653145 | 0.79 | CTNNB1 (0.36) | APPPOLBCTNNB1TCF7L2NPC1 | |
| SCHEMBL28054684 | 0.72 | KDM4E (0.47) | APPKMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7653573 | 0.71 | APP (0.52) | SMN1; SMN2APPPOLBL3MBTL1KMT2A | |
| SCHEMBL6650864 | 0.70 | TP53 (0.51) | SMN1; SMN2APPPOLBL3MBTL1KMT2A | |
| SCHEMBL7649849 | 0.69 | KMT2A (0.55) | SMN1; SMN2APPPOLBKMT2ALMNA | |
| SCHEMBL7553839 | 0.69 | APP (0.49) | SMN1; SMN2APPPOLBL3MBTL1KMT2A | |
| SCHEMBL6651230 | 0.67 | APP (0.47) | SMN1; SMN2APPPOLBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158299-C | 4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, method fo r producing the same, medicaments containing these compounds and their use | ���ĵ�˹ҩ��¹�����˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1374968-A | 4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, method fo r producing the same, medicaments containing these compounds and their use | AVENTIS PHARMA PEUTSCHLAND GMB (DE) | 2002-10-16 | — | — | CN | disclosed |