Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ASPH | Q12797 | 2/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617925 | 0.89 | MAPT (0.51) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7654278 | 0.80 | MEN1 (0.42) | KDM4EAPPMEN1KMT2AALDH1A1 | |
| SCHEMBL6652586 | 0.74 | KMT2A (0.60) | KDM4EAPPMEN1KMT2AALDH1A1 | |
| SCHEMBL7554973 | 0.73 | APP (0.39) | APPMEN1KMT2AMAPTPPARA | |
| SCHEMBL6653145 | 0.72 | CTNNB1 (0.36) | APPMEN1KMT2AMAPT | |
| SCHEMBL27464342 | 0.72 | SMN1; SMN2 (0.41) | APPMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL3115205 | 0.71 | CCNE2 (0.51) | APPEGFRACP1 | |
| SCHEMBL7653573 | 0.71 | APP (0.52) | APPMEN1KMT2AALDH1A1 | |
| SCHEMBL27464341 | 0.71 | CTNNB1 (0.37) | KDM4EAPPMEN1KMT2AALDH1A1 | |
| SCHEMBL24987203 | 0.70 | KDM4E (0.50) | KDM4EASPHKDM8EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106107406-A | Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers | 赛诺米克斯公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-103153096-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 赛诺米克斯公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102933081-B | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-04-13 | — | — | CN | disclosed |
| CN-103153096-A | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | SENOMYX INC | 2013-06-12 | — | — | CN | disclosed |