Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649849 | 0.84 | KMT2A (0.55) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL6653145 | 0.83 | CTNNB1 (0.36) | MEN1KMT2ATP53MAPTCTNNB1 | |
| SCHEMBL617925 | 0.82 | MAPT (0.51) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27464341 | 0.82 | CTNNB1 (0.37) | MEN1KMT2ATP53MAPTCTNNB1 | |
| SCHEMBL7554973 | 0.82 | APP (0.39) | MEN1KMT2ATP53MAPTCTNNB1 | |
| SCHEMBL27464342 | 0.80 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2CTNNB1TCF7L2 | |
| SCHEMBL28054684 | 0.80 | KDM4E (0.47) | MEN1KMT2AMAPTAPPALDH1A1 | |
| SCHEMBL7651486 | 0.77 | PRNP (0.50) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7646678 | 0.76 | KMT2A (0.61) | MEN1KMT2ATP53SMN1; SMN2APP | |
| SCHEMBL7646312 | 0.74 | APP (0.46) | MEN1KMT2ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339077-B1 | FOR PROPHYLAXIS OR OF GALLSTONES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-15 | — | — | US | disclosed |