Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158379 | 0.83 | ALDH1A1 (0.52) | NPSR1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL8086014 | 0.81 | ALDH1A1 (0.55) | NPSR1ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL31553215 | 0.72 | NPSR1 (0.50) | NPSR1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL984055 | 0.72 | LTA4H (0.67) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL10843932 | 0.72 | LTA4H (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL28593997 | 0.71 | LMNA (0.61) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8577094 | 0.71 | SMN1; SMN2 (0.61) | NPSR1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL8934551 | 0.71 | VKORC1 (0.66) | ALDH1A1HPGDKDM4ECYP19A1 | |
| SCHEMBL304562 | 0.71 | KDM4E (0.61) | NPSR1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28174587 | 0.71 | LTA4H (0.56) | NPSR1ALDH1A1LMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138458-A | Treatment and prevention of prostatic cancer | LILLY CO ELI (US) | 1996-12-25 | — | — | CN | disclosed |