SCHEMBL27465752

SCHEMBL27465752

COc1cc(C)c(C(=O)c2ccccc2)c(OCCC(C)C)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CCNB2 O95067 1/20 0.45
CCNE2 O96020 1/20 0.45
CDK1 P06493 1/20 0.45
CCNB1 P14635 1/20 0.45
CCNE1 P24864 1/20 0.45
CDK2 P24941 1/20 0.45
CDK7 P50613 1/20 0.45
CCNH P51946 1/20 0.45
CCNB3 Q8WWL7 1/20 0.45
ATM Q13315 2/20 0.43
KMT2A Q03164 3/20 0.41
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150755 0.85 L3MBTL1 (0.40) LMNAMAPTL3MBTL1KMT2AGAA
SCHEMBL27453484 0.84 LMNA (0.46) LMNAMAPTL3MBTL1CCNB2CCNE2
SCHEMBL7517866 0.83 KCNB1 (0.39) LMNAMAPTL3MBTL1KMT2AGAA
SCHEMBL7943881 0.83 ATM (0.54) LMNAMAPTATMKMT2APTGS1
SCHEMBL7626410 0.73 KMT2A (0.43) LMNAMAPTL3MBTL1KMT2AGAA
SCHEMBL8466591 0.73 TUBB4A (0.43) LMNAMAPTL3MBTL1ATMKMT2A
SCHEMBL6693650 0.72 PDE4A (0.52) LMNAATM
SCHEMBL6150798 0.71 L3MBTL1 (0.44) LMNAMAPTL3MBTL1KMT2AGAA
SCHEMBL7522504 0.71 KCNB1 (0.42) LMNAMAPTL3MBTL1KMT2AALDH1A1
SCHEMBL6149687 0.71 RAB9A (0.42) LMNAMAPTL3MBTL1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1159278-C Fungicidal methods, compounds and compositions contg. benzophenones 2004-07-28 CN claimed
CN-1134929-A Fungicidal methods, compounds and compositions contg. benzophenones AMERICAN CYANAMID CO (US) 1996-11-06 CN claimed
CN-1159278-C Fungicidal methods, compounds and compositions contg. benzophenones 2004-07-28 CN disclosed
CN-1134929-A Fungicidal methods, compounds and compositions contg. benzophenones AMERICAN CYANAMID CO (US) 1996-11-06 CN disclosed