Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628968 | 0.86 | MEN1 (0.46) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL8706000 | 0.84 | TSHR (0.44) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL8706005 | 0.81 | MEN1 (0.40) | L3MBTL1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7626374 | 0.72 | MEN1 (0.40) | MEN1KMT2ATSHRRAB9ASMN1; SMN2 | |
| SCHEMBL867886 | 0.72 | L3MBTL1 (1.00) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL8699309 | 0.72 | TSHR (0.39) | ATML3MBTL1MEN1KMT2ATSHR | |
| Benzene SCHEMBL27466605 | 0.71 | ALDH1A1 (0.48) | ATMNPSR1MEN1KMT2ARAB9A | |
| SCHEMBL6965290 | 0.71 | ALDH1A1 (0.48) | ATMNPSR1MEN1KMT2ARAB9A | |
| SCHEMBL21729903 | 0.71 | L3MBTL1 (0.76) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL8699460 | 0.71 | TSHR (0.39) | L3MBTL1MEN1KMT2ATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152015-C | Piperazine devivatives and process for preparation thereof | ������ҩ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| CN-1196724-A | Novel piperazine derivative and process for producing the same | SAMJIN PHARM CO LTD (KR) | 1998-10-21 | — | — | CN | disclosed |