Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416376 | 0.70 | ALOX15 (0.39) | SMN1; SMN2L3MBTL1ALDH1A1MAPTOPRM1 | |
| SCHEMBL22965244 | 0.65 | ALOX5 (0.49) | SMN1; SMN2ALDH1A1HSD17B10MAPT | |
| SCHEMBL11152068 | 0.62 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30936629 | 0.62 | LMNA (0.40) | ALDH1A1HSD17B10LMNAPABPC1MAPT | |
| SCHEMBL6865172 | 0.62 | ALDH1A1 (0.63) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL10455457 | 0.62 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL31520096 | 0.62 | ALDH1A1 (0.63) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL19718781 | 0.62 | SMYD3 (0.40) | SMN1; SMN2L3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL8564451 | 0.61 | GAA (0.41) | ALDH1A1HSD17B10LMNAPABPC1MAPT | |
| SCHEMBL20338996 | 0.61 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152866-C | Benzimidazoles, production thereof and use thereof medicaments | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1308614-A | Benzimidazoles, production thereof and use thereof medicaments | BOEHRINGER INGELHEIM PHAMA KG (DE) | 2001-08-15 | — | — | CN | disclosed |