SCHEMBL27467296

SCHEMBL27467296

Cc1ccc(C(=O)N(c2ccc(F)c([Ti])c2F)C2CCCCC2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ABCC1 P33527 1/20 0.35
TP53 P04637 2/20 0.35
MAPT P10636 1/20 0.35
GLA P06280 1/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 2/20 0.33
SLC6A9 P48067 1/20 0.33
PDK2 Q15119 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
S1PR1 P21453 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27482848 0.87 LMNA (0.45) LMNAMEN1KMT2AHDAC1HDAC6
SCHEMBL27467773 0.78 SLC6A9 (0.45) LMNAMEN1KMT2AALDH1A1NPC1
SCHEMBL27482480 0.78 HPGD (0.52) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL4621748 0.77 ALDH1A1 (0.46) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL27559906 0.71 RIPK1 (0.34) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL27482135 0.70 ALDH1A1 (0.33) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL14147025 0.67 TRPM8 (0.48) LMNAMEN1KMT2AABCC1NPC1
SCHEMBL27498015 0.67 ESR1 (0.35) MEN1KMT2ATP53MAPTNPSR1
SCHEMBL20460518 0.66 PDK2 (0.62) MEN1KMT2AABCC1TP53NPC1
SCHEMBL11590734 0.65 HTT (0.38) LMNAMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1171122-C Optical polymerism composition 富士胶片株式会社 2004-10-13 CN disclosed
CN-1319784-A Optical polymerism composition FUJI PHOTO FILM CO LTD (JP) 2001-10-31 CN disclosed