Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467150 | 0.80 | FFAR2 (0.63) | EPHX2FFAR2GCK | |
| SCHEMBL27515306 | 0.78 | FFAR1 (0.45) | FFAR2 | |
| SCHEMBL27552958 | 0.77 | SLC6A3 (0.38) | MEN1KMT2A | |
| SCHEMBL27482051 | 0.70 | SLC6A3 (0.37) | — | |
| SCHEMBL27465638 | 0.69 | GCK (0.60) | EPHX2POLBFFAR2GCK | |
| SCHEMBL27482753 | 0.69 | GCK (0.60) | EPHX2POLBFFAR2GCK | |
| SCHEMBL27466236 | 0.69 | GCK (0.59) | EPHX2POLBFFAR2GCK | |
| SCHEMBL2645075 | 0.66 | FFAR2 (0.72) | EPHX2POLBFFAR2GCKMAPT | |
| SCHEMBL2645076 | 0.66 | FFAR2 (0.72) | EPHX2POLBFFAR2GCKMAPT | |
| SCHEMBL2657079 | 0.66 | FFAR2 (0.72) | EPHX2POLBFFAR2GCKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | claimed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | claimed |
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |