Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515306 | 0.89 | FFAR1 (0.45) | SLC6A3METAP2SLC6A2SLC6A4FFAR1 | |
| SCHEMBL27482051 | 0.81 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27468087 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2A | |
| SCHEMBL27616381 | 0.76 | KCNH2 (0.45) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL27465660 | 0.74 | SLC6A3 (0.40) | SLC6A3METAP2SLC6A2SLC6A4 | |
| SCHEMBL27466230 | 0.72 | APP (0.42) | SLC6A3METAP2SLC6A2SLC6A4 | |
| SCHEMBL9155662 | 0.71 | MEN1 (0.47) | METAP2MEN1KMT2AFFAR1EPHX1 | |
| SCHEMBL17761361 | 0.70 | FFAR1 (0.50) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL12836112 | 0.70 | FFAR1 (0.50) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL17761387 | 0.70 | FFAR1 (0.50) | SLC6A3SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |