Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552958 | 0.89 | SLC6A3 (0.38) | FFAR1SLC6A3SLC6A2SLC6A4METAP2 | |
| SCHEMBL27482051 | 0.81 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27468087 | 0.78 | ALDH1A1 (0.46) | FFAR2 | |
| SCHEMBL4249915 | 0.76 | FFAR1 (0.60) | FFAR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27466230 | 0.76 | APP (0.42) | SLC6A3SLC6A2SLC6A4METAP2 | |
| SCHEMBL27467646 | 0.76 | KCNH2 (0.46) | FFAR1SLC6A3PTGS2SLC6A2SLC6A4 | |
| SCHEMBL27502236 | 0.76 | KCNH2 (0.46) | FFAR1SLC6A3PTGS2SLC6A2SLC6A4 | |
| SCHEMBL27465660 | 0.74 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4METAP2 | |
| SCHEMBL14798077 | 0.74 | FFAR1 (0.49) | FFAR1SLC6A3PTGS2SLC6A2SLC6A4 | |
| SCHEMBL15971818 | 0.72 | FFAR1 (0.49) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |