Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784924 | 0.86 | DPP4 (0.59) | DPP4ALDH1A1L3MBTL1NPSR1LTA4H | |
| SCHEMBL4596133 | 0.82 | MAPK1 (0.59) | ALDH1A1L3MBTL1MAPK1HTTLTA4H | |
| SCHEMBL197298 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1L3MBTL1MAPK1NPSR1LMNA | |
| SCHEMBL9139036 | 0.79 | HTT (0.50) | DPP4ALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL10499349 | 0.78 | LMNA (0.48) | DPP4ALDH1A1L3MBTL1MAPK1HTT | |
| Ethane SCHEMBL27569819 | 0.78 | DPP4 (0.58) | DPP4ALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL6900858 | 0.78 | ALDH1A1 (0.48) | DPP4ALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL9645022 | 0.78 | LTA4H (0.52) | DPP4ALDH1A1NPSR1LTA4HLMNA | |
| SCHEMBL3790160 | 0.78 | DPP4 (0.62) | DPP4ALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL18354030 | 0.77 | DPP4 (0.50) | DPP4ALDH1A1L3MBTL1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216052-C | Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz (b,f) oxepines | NAVARTIS AG (CH) | 2005-08-24 | — | — | CN | disclosed |
| CN-1137039-A | Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz (b,f) oxepines | CIBA GEIGY AG (CH) | 1996-12-04 | — | — | CN | disclosed |