SCHEMBL2746909

SCHEMBL2746909

CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)C(N)CCCCN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
TP53 P04637 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2D6 P10635 1/20 1.00
MAPT P10636 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
GNAI3 P08754 1/20 0.51
GNAO1 P09471 1/20 0.51
GNAI1 P63096 1/20 0.51
GALR3 O60755 1/20 0.45
TLR2 O60603 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469077 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9469286 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9469673 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9468782 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9468961 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9469386 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9468929 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9468950 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9468818 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9469806 1.00 MEN1 (1.00) MEN1KMT2ATP53CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120238019-A1 STEM CELL CULTURE MEDIA FOR MAINTAINING STEMNESS OR INDUCING DIFFERENTIATION OF STEM CELLS COLLEGE OF MEDICINE POCHON CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2012-09-20 US claimed
US-20080234380-A1 Compositions and method for treatment of chronic inflammatory diseases SHAPIRO HOWARD K 2008-09-25 US claimed
US-5189046-A Antiinflammatory agents, anticonvulsants NOVA PHARMACEUTICAL CORPORATION (US) 1993-02-23 US claimed
WO-1992003415-A1 PROTEIN KINASE C MODULATORS NOVA PHARMACEUTICAL CORPORATION (US) 1992-03-05 WO claimed
US-20250032530-A1 USE OF AURANOFIN AS AN INHIBITOR OF ATYPICAL PROTEIN KINASE C FOR TREATMENT OF NEURODEGENERATIVE DISORDERS UNIVERSITY OF SOUTH FLORIDA 2025-01-30 US disclosed
US-20250000821-A1 METHODS OF USING DIPIVEFRIN Insignis Therapeutics, Inc. 2025-01-02 US disclosed
US-20240389587-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2024-11-28 US disclosed
EP-4440313-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS Institut national de recherche pour l'agriculture, L'alimentation et l'environnement (INRAE) (FR) 2024-10-09 EP disclosed
CN-118714927-A Compositions and methods for controlling phytopathogenic infection 法国国家农业食品与环境研究院 2024-09-27 CN disclosed
US-20230288429-A1 REAL TIME ELECTRONIC CELL SENSING SYSTEMS AND APPLICATIONS FOR CELL-BASED ASSAYS AGILENT TECHNOLOGIES, INC. 2023-09-14 US disclosed
CN-111565716-B Method of using dipivefrin 因斯格尼斯疗法有限公司 2023-06-09 CN disclosed
WO-2023099609-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2023-06-08 WO disclosed
US-20050090553-A1 Compositions and method for treatment of chronic inflammatory diseases SECANT PHARMA, LLC 2005-04-28 US disclosed
EP-1503735-A2 A DIRECT CELLULAR ENERGY DELIVERY SYSTEM University of Louisville Research Foundation, Inc. (US) 2005-02-09 EP disclosed
WO-2003096973-A2 A DIRECT CELLULAR ENERGY DELIVERY SYSTEM UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2003-11-27 WO disclosed
EP-0759750-A4 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1998-05-27 EP disclosed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP disclosed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO disclosed
US-5189046-A Antiinflammatory agents, anticonvulsants NOVA PHARMACEUTICAL CORPORATION (US) 1993-02-23 US disclosed
WO-1992003415-A1 PROTEIN KINASE C MODULATORS NOVA PHARMACEUTICAL CORPORATION (US) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250000821-A1 METHODS OF USING DIPIVEFRIN QDPR, DNPEP, DPEP1 MEN1 419/4885KMT2A 3596/4885TP53 1584/4885
US-20050090553-A1 Compositions and method for treatment of chronic inflammatory diseases PCCA, HMGB1, PTGES MEN1 4876/4885KMT2A 1830/4885TP53 1236/4885
US-20080234380-A1 Compositions and method for treatment of chronic inflammatory diseases HMGB1, PCCA, QSOX1 MEN1 4870/4885KMT2A 1426/4885TP53 1288/4885
US-20240389587-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS XBP1, ERN1, ERN2 MEN1 3635/4885KMT2A 4467/4885TP53 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.