Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418964 | 0.79 | MAPT (0.44) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL14188336 | 0.78 | ALKBH5 (0.48) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| Iodide SCHEMBL6250148 | 0.78 | MAPT (0.43) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL16046643 | 0.74 | ALKBH5 (0.39) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL20746871 | 0.73 | ALKBH5 (0.38) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL862529 | 0.72 | MAPT (0.43) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL4421580 | 0.69 | MAPT (0.63) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL22181379 | 0.69 | MAPT (0.63) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL28434877 | 0.69 | SLC9A1 (0.41) | ALKBH5FTOMAPTKDM4EALDH1A1 | |
| SCHEMBL28868133 | 0.69 | ALDH1A1 (0.40) | ALKBH5FTOMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085556-A | The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine | BRISTOL MYERS SQUIBB CO (US) | 1994-04-20 | — | — | CN | disclosed |