SCHEMBL2747178

SCHEMBL2747178

O=C(O)c1c(C#Cc2ccccc2)cccc1C(F)(c1cccc(C#Cc2ccccc2)c1C(=O)O)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HAO1 Q9UJM8 1/20 0.35
LMNA P02545 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746374 0.80 NPC1 (0.45) FFAR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL2747181 0.78 HNF4A (0.40) FFAR1NPC1RAB9AALDH1A1MEN1
SCHEMBL5025935 0.75 NPC1 (0.41) FFAR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL2747867 0.75 NPC1 (0.53) FFAR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL5186678 0.74 CA12 (0.53) KDM4EALDH1A1HPGDSMN1; SMN2CA12
SCHEMBL3423138 0.74 TAS2R14 (0.40) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL10807357 0.72 CA12 (0.55) FFAR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL38694 0.72 NPC1 (0.59) FFAR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL2747573 0.72 FFAR1 (0.39) FFAR1SMN1; SMN2LMNAPTGDR2
SCHEMBL2747155 0.69 FFAR1 (0.42) FFAR1NPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed