SCHEMBL2747181

SCHEMBL2747181

O=C(O)c1cccc(C(F)(c2cccc(C(=O)O)c2C#Cc2ccccc2)C(F)(F)C(F)(F)F)c1C#Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
TAS2R14 Q9NYV8 3/20 0.37
PTPRC P08575 4/20 0.36
PTPN2 P17706 4/20 0.36
PTPN1 P18031 4/20 0.36
PTPN6 P29350 4/20 0.36
PTPN9 P43378 4/20 0.36
DUSP3 P51452 4/20 0.36
PTPN11 Q06124 4/20 0.36
PTPN22 Q9Y2R2 4/20 0.36
EPM2A O95278 2/20 0.36
PTPRG P23470 2/20 0.36
ACP1 P24666 2/20 0.36
PTPN7 P35236 2/20 0.36
PTPN13 Q12923 2/20 0.36
DUSP22 Q9NRW4 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747575 0.82 TAS2R14 (0.38) TAS2R14PTPRCPTPN9PTPN11PTPN22
SCHEMBL5669586 0.80 HNF4A (0.44) HNF4ANPC1RAB9AAKR1C2AKR1C1
SCHEMBL1372606 0.78 ALDH1A1 (0.48) AKR1C2TAS2R14FABP4ALDH1A1ALOX15
SCHEMBL1713009 0.78 HNF4A (0.55) HNF4ANPC1RAB9AAKR1C2AKR1C1
SCHEMBL2747178 0.78 FFAR1 (0.43) HNF4ANPC1RAB9APTPN1PTPN11
SCHEMBL5669173 0.76 PTPN11 (0.43) HNF4AAKR1C2AKR1C1PTPRCPTPN2
SCHEMBL5025935 0.75 NPC1 (0.41) NPC1RAB9ATAS2R14FABP4FFAR1
SCHEMBL3423138 0.74 TAS2R14 (0.40) TAS2R14FABP4ALDH1A1ALOX15NAPRT
SCHEMBL7150816 0.74 ALB (0.50) HNF4ATAS2R14FABP4ALDH1A1ALOX15
SCHEMBL5667352 0.74 HNF4A (0.50) HNF4ANPC1RAB9AAKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed