SCHEMBL3423138

SCHEMBL3423138

O=C(O)c1cccc(C(F)(c2cccc(C(=O)O)c2C(=O)O)C(F)(F)C(F)(F)F)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 2/20 0.40
FABP4 P15090 1/20 0.39
ALDH1A1 P00352 4/20 0.39
ALOX15 P16050 3/20 0.39
ALB P02768 1/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
AKR1C3 P42330 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096331 0.85 TAS2R14 (0.39) TAS2R14FABP4ALDH1A1ALOX15ALB
SCHEMBL7095723 0.84 ALOX15 (0.43) TAS2R14FABP4ALDH1A1ALOX15ALB
SCHEMBL1372606 0.84 ALDH1A1 (0.48) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL7092199 0.83 TAS2R14 (0.38) TAS2R14FABP4ALDH1A1ALOX15ALB
SCHEMBL7091349 0.83 TAS2R14 (0.38) TAS2R14FABP4ALDH1A1ALOX15ALB
SCHEMBL5186678 0.83 CA12 (0.53) ALDH1A1KDM4EHPGDCA12CA1
SCHEMBL7150816 0.83 ALB (0.50) TAS2R14FABP4ALDH1A1ALOX15ALB
SCHEMBL6003827 0.82 HTT (0.40) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL30269555 0.82 TAS2R14 (0.42) TAS2R14FABP4ALDH1A1ALOX15ALB
SCHEMBL145576 0.82 TAS2R14 (0.42) TAS2R14FABP4ALDH1A1ALOX15ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150030887-A1 MAGNETIC DEVICES WITH MOLECULAR OVERCOATS SEAGATE TECHNOLOGY LLC (US) 2015-01-29 US claimed
EP-0328027-B1 Novel soluble polyimidesiloxanes and methods for their preparation and use OCCIDENTAL CHEM CO (US) 1995-09-20 EP claimed
EP-0328027-A2 Novel soluble polyimidesiloxanes and methods for their preparation and use OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-16 EP claimed
US-4853452-A Novel soluble polyimidesiloxanes and methods for their preparation using a flourine containing anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-01 US claimed
CN-109863206-A Resin combination, resin sheet, cured film, organic EL display device, semiconductor electronic part, semiconductor devices and organic EL display device manufacturing method 东丽株式会社 2019-06-07 CN disclosed
CN-104662475-B The manufacturing method of positive type photosensitive organic compound, semiconductor devices containing the cured film for having used it 东丽株式会社 2019-03-29 CN disclosed
CN-109313387-A Photosensitive polymer combination 东丽株式会社 2019-02-05 CN disclosed
US-10020011-B2 Devices including an amorphous gas barrier layer SEAGATE TECHNOLOGY LLC (US) 2018-07-10 US disclosed
EP-2218754-B1 POLYIMIDE COMPOSITE MATERIAL AND FILM OF THE SAME MITSUI CHEMICALS INC (JP) 2018-06-20 EP disclosed
US-20170213570-A1 DEVICES INCLUDING AN AMORPHOUS GAS BARRIER LAYER SEAGATE TECHNOLOGY LLC (US) 2017-07-27 US disclosed
US-9691520-B2 Method for preparing polymer-nanoparticles having core-shell structure by uniformly coating polymer on metal and inorganic particles, polymer-nanoparticles prepared thereby, and polymer-nanoparticle composite comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2017-06-27 US disclosed
US-20170125043-A1 DEVICES INCLUDING A MULTILAYER GAS BARRIER LAYER SEAGATE TECHNOLOGY LLC (US) 2017-05-04 US disclosed
US-5480965-A BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0328027-B1 Novel soluble polyimidesiloxanes and methods for their preparation and use OCCIDENTAL CHEM CO (US) 1995-09-20 EP disclosed
EP-0639621-A2 Polyimide-based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-02-22 EP disclosed
US-5206337-A Heat resistance, moldability, workability SUMITOMO BAKELITE COMPANY LIMITED (JP) 1993-04-27 US disclosed
EP-0456512-A2 Polyimidesiloxane oligomer SUMITOMO BAKELITE COMPANY LIMITED (JP) 1991-11-13 EP disclosed
EP-0392680-A2 Aromatic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-17 EP disclosed
EP-0328027-A2 Novel soluble polyimidesiloxanes and methods for their preparation and use OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-16 EP disclosed
US-4853452-A Novel soluble polyimidesiloxanes and methods for their preparation using a flourine containing anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-01 US disclosed