Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311610 | 0.84 | ALDH1A1 (0.71) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL418527 | 0.82 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL69953 | 0.82 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6786850 | 0.81 | HTT (0.68) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL31498242 | 0.80 | MGAM (0.61) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL7565802 | 0.80 | MGAM (0.61) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL72201 | 0.79 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL27739759 | 0.79 | ALDH1A1 (0.58) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL30620060 | 0.78 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9095415 | 0.78 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1173954-C | Compounds, compositions and methods for generating chemiluminescence by reaction with phosphatases | 3 | 2004-11-03 | — | — | CN | disclosed |
| CN-1312252-A | Intermediate of chemical compound generating chemical illumination when reacts with phosphatase | RUMIGEN CO (US) | 2001-09-12 | — | — | CN | disclosed |
| CN-1180349-A | Compounds, compositions and methods for generating chemiluminescence by reaction with phosphatases | LUMIGEN INC (US) | 1998-04-29 | — | — | CN | disclosed |