Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69953 | 0.81 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5174792 | 0.79 | TDP1 (0.53) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28992464 | 0.79 | MAPT (0.66) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23081015 | 0.78 | HTT (0.56) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27472012 | 0.78 | MAPT (0.60) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL418527 | 0.77 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL72201 | 0.77 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12311610 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29637878 | 0.76 | MAPT (0.57) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10960357 | 0.76 | MAPT (0.57) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940572-A | 2H-indazole derivatives as IRAK4 inhibitors and their use in the treatment of diseases | 渤健马萨诸塞州股份有限公司 | 2023-10-24 | — | — | CN | disclosed |