Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 9/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.40 |
| ▸ | GABRP | O00591 | 4/20 | 0.40 |
| ▸ | GABRD | O14764 | 4/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | GABRE | P78334 | 4/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486965 | 0.86 | KDM4E (0.41) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL27907009 | 0.82 | KDM4E (0.44) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL2558805 | 0.81 | HPGDS (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL27803032 | 0.78 | HPGDS (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL14957462 | 0.77 | NAPRT (0.48) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL27788813 | 0.76 | GABRP (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL28085715 | 0.75 | GABRP (0.44) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL27487328 | 0.74 | ALDH1A1 (0.50) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL27946211 | 0.74 | LMNA (0.34) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL28251522 | 0.73 | CA12 (0.35) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522961-C | Amide substituted xanthine derivatives with gluconeogenesis modulating activity | HOFFMANN LA ROCHE (CH) | 2009-08-05 | — | — | CN | disclosed |
| CN-1659168-A | Amide-substituted xanthine derivatives having gluconeogenesis modulating activity | HOFFMANN LA ROCHE (CH) | 2005-08-24 | — | — | CN | disclosed |
| CN-1522698-A | Antivirals | ά | 2004-08-25 | — | — | CN | disclosed |
| CN-1158261-C | Antiviral medicine | ά | 2004-07-21 | — | — | CN | disclosed |
| CN-1292781-A | Antiviral medicine | MEDIVIR AB (SE) | 2001-04-25 | — | — | CN | disclosed |