Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948935 | 0.77 | CES1 (0.46) | CES1MLYCDPOLBTSHRTDP1 | |
| SCHEMBL27513365 | 0.74 | CES1 (0.43) | CES1MLYCDPOLBTSHRNR1H3 | |
| SCHEMBL6505102 | 0.73 | CES1 (0.37) | CES1MLYCDPOLBCYP3A4PARP1 | |
| SCHEMBL9731004 | 0.70 | CES1 (0.45) | CES1MLYCDPOLBCYP3A4PARP1 | |
| SCHEMBL28760310 | 0.70 | CYP2C19 (0.42) | CES1CYP2C19TDP1ALDH1A1 | |
| Benzamide SCHEMBL3994635 | 0.68 | PARP1 (0.57) | CES1POLBCYP3A4PARP1MAPT | |
| SCHEMBL28173074 | 0.68 | ALDH1A1 (0.43) | CES1MLYCDMAPTHSD17B10TDP1 | |
| SCHEMBL7202702 | 0.67 | TSHR (0.50) | CES1POLBCYP3A4PARP1MAPT | |
| SCHEMBL8778288 | 0.67 | LMNA (0.54) | CES1POLBMAPTTSHRHSD17B10 | |
| SCHEMBL9956627 | 0.67 | CES1 (0.50) | CES1MLYCDPOLBCYP3A4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1181070-C | Urea substituted imidazoquinolines | 3M | 2004-12-22 | — | — | CN | disclosed |
| CN-1355701-A | Urea substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2002-06-26 | — | — | CN | disclosed |