Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.46 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539445 | 0.82 | CNR1 (0.44) | CASRALDH1A1DRD3 | |
| SCHEMBL7540512 | 0.82 | DRD2 (0.41) | HDAC3CASRALDH1A1HDAC1DRD3 | |
| SCHEMBL381765 | 0.82 | ALDH1A1 (0.46) | CASRALDH1A1HDAC1DRD3 | |
| SCHEMBL382963 | 0.82 | SMYD3 (0.43) | HDAC3CASRALDH1A1HDAC1DRD3 | |
| SCHEMBL6796225 | 0.82 | CASR (0.44) | CASRDRD3 | |
| SCHEMBL6800155 | 0.80 | ALDH1A1 (0.44) | CASRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6799964 | 0.80 | DRD2 (0.39) | HDAC3CASRALDH1A1HDAC1DRD3 | |
| SCHEMBL6796554 | 0.79 | ITGB3 (0.49) | CASRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7540509 | 0.78 | CASR (0.42) | CASRDRD3 | |
| SCHEMBL28747046 | 0.78 | ITGB3 (0.49) | CASRMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140511-C | As integrin alphavβ3Aminopiperidine derivatives as antagonists | �����Ƹ���ʽ���� | 2004-03-03 | — | — | CN | disclosed |