Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799962 | 0.92 | CASR (0.40) | CASRHPGDSITGB3ITGAVITGA2B | |
| SCHEMBL6800147 | 0.91 | ITGB3 (0.45) | CASRHPGDSITGB3ITGAVITGA2B | |
| SCHEMBL6796225 | 0.84 | CASR (0.44) | CASRHPGDSITGB3ITGAVITGA2B | |
| SCHEMBL6801434 | 0.83 | ITGB3 (0.43) | CASRHPGDSITGB3ITGAVITGA2B | |
| SCHEMBL381765 | 0.81 | ALDH1A1 (0.46) | CASRHPGDSDRD2DRD3CNR1 | |
| SCHEMBL7540526 | 0.81 | DRD2 (0.41) | CASRITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL6800173 | 0.80 | CASR (0.43) | CASRITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL6800155 | 0.80 | ALDH1A1 (0.44) | CASRHPGDSITGB3ITGAVITGA2B | |
| SCHEMBL6799981 | 0.80 | DRD2 (0.40) | CASRHPGDSITGB3ITGAVITGA2B | |
| SCHEMBL381767 | 0.79 | ITGB3 (0.51) | CASRITGB3ITGAVITGA2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209152-A1 | OMEGA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-05-29 | — | — | EP | claimed |
| EP-1209152-A1 | OMEGA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-05-29 | — | — | EP | disclosed |