Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.57 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382123 | 0.86 | KDM4E (0.57) | KDM4ESMN1; SMN2TP53HSD17B10TARBP2 | |
| SCHEMBL22678558 | 0.85 | KDM4E (0.56) | KDM4ESMN1; SMN2TP53HSD17B10TARBP2 | |
| SCHEMBL27475261 | 0.85 | PIN1 (0.68) | KDM4ESMN1; SMN2TP53HSD17B10TARBP2 | |
| SCHEMBL8964177 | 0.83 | PIN1 (0.56) | KDM4ESMN1; SMN2GAAMAPTNPC1 | |
| SCHEMBL17803252 | 0.82 | KDM4E (0.58) | KDM4ESMN1; SMN2TP53HSD17B10MAPT | |
| SCHEMBL28297288 | 0.81 | GAA (0.58) | KDM4ESMN1; SMN2TP53HSD17B10TARBP2 | |
| SCHEMBL8964001 | 0.81 | PIN1 (0.51) | KDM4ESMN1; SMN2TP53GAAHCRTR1 | |
| SCHEMBL7988102 | 0.79 | MAPT (0.54) | SMN1; SMN2TARBP2PDCD4POLBGAA | |
| SCHEMBL11863144 | 0.79 | MAPT (0.49) | KDM4ESMN1; SMN2TP53HSD17B10TARBP2 | |
| SCHEMBL7989867 | 0.78 | SIRT2 (0.58) | SMN1; SMN2TP53TARBP2PDCD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |