Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479611 | 0.85 | PTPN1 (0.55) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL27761066 | 0.83 | ALDH1A1 (0.64) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL8060457 | 0.81 | EGFR (0.75) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL8060454 | 0.81 | EGFR (0.75) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL5950432 | 0.77 | GRIK1 (0.78) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL27782781 | 0.77 | CXCR1 (0.54) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL5950332 | 0.76 | GRIK1 (0.78) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL420926 | 0.74 | TRPM2 (0.74) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL420925 | 0.74 | TRPM2 (0.74) | ALDH1A1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL8065883 | 0.74 | TRPA1 (0.75) | ALDH1A1NPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190963-A | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 1998-08-19 | — | — | CN | disclosed |