Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592349 | 0.86 | TSHR (0.54) | CFDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL11989069 | 0.82 | KDM4E (0.50) | CFDALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL23618507 | 0.82 | CFD (0.48) | CFDALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL1554320 | 0.81 | KDM4E (0.53) | CFDALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL7039814 | 0.81 | ALDH1A1 (0.49) | CFDALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL10747363 | 0.81 | TSHR (0.47) | ALDH1A1KDM4EMAPTGAAHSD17B10 | |
| SCHEMBL7040734 | 0.81 | CFD (0.50) | CFDALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9724473 | 0.80 | CXCL8 (0.57) | CFDALDH1A1NR1H4HPGD | |
| SCHEMBL7039813 | 0.80 | MASP2 (0.54) | CFDALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL1953684 | 0.80 | MAPT (0.62) | ALDH1A1MAPTGAAGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143362-A | Novel benzodizaepine derivative | SHIONOGI & CO (JP) | 1997-02-19 | — | — | CN | disclosed |