Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 4/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189905 | 0.80 | TSHR (0.48) | HTTMAPK1TSHRGAAKMT2A | |
| SCHEMBL8700635 | 0.77 | SLC1A5 (0.45) | SLC1A5PTGER1GAAHTR1ADRD2 | |
| SCHEMBL8162048 | 0.76 | PTGER1 (0.50) | HTTMAPK1RXRARXRBRXRG | |
| SCHEMBL27428219 | 0.75 | GAA (0.50) | HTTMAPK1RXRARXRBRXRG | |
| SCHEMBL8706840 | 0.74 | CCR5 (0.51) | HTTPTGER1 | |
| SCHEMBL9055416 | 0.73 | TSPO (0.48) | HTTSLC1A5GAASGMS2KMT2A | |
| SCHEMBL8162045 | 0.72 | PTGER1 (0.56) | HTTMAPK1RXRARXRBRXRG | |
| Bicarbonate SCHEMBL27963003 | 0.71 | HTR1A (0.61) | HTTMAPK1RXRARXRBRXRG | |
| SCHEMBL8699954 | 0.71 | KMT2A (0.48) | HTTRXRARXRBRXRGSLC1A5 | |
| SCHEMBL28177697 | 0.70 | HCRTR1 (0.54) | HTTMAPK1GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085663-C | Aromatic amino ethers as analgesic agents | ZENECA LTD (GB) | 2002-05-29 | — | — | CN | disclosed |
| CN-1286254-A | Aromatic amino ethers as analgesic agents | ZENECA LTD (GB) | 2001-03-07 | — | — | CN | disclosed |
| CN-1154106-A | Aromatic amino ethers as analgesic agents | ZENECA LTD (GB) | 1997-07-09 | — | — | CN | disclosed |