Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333220 | 0.81 | KMT2A (0.50) | GAAL3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL6358805 | 0.80 | SGMS2 (0.61) | GAASGMS2PTGER1LMNAMAPT | |
| SCHEMBL8167588 | 0.80 | LMNA (0.53) | GAASGMS2PTGER1LMNAMAPT | |
| SCHEMBL5778368 | 0.78 | ALDH1A1 (0.53) | GAASGMS2PTGER1LMNAMAPT | |
| SCHEMBL5305401 | 0.76 | LMNA (0.60) | GAASGMS2PTGER1LMNAMAPT | |
| SCHEMBL27480606 | 0.75 | HTT (0.44) | GAASGMS2PTGER1MAPTL3MBTL1 | |
| SCHEMBL6358385 | 0.75 | SGMS2 (0.73) | GAASGMS2LMNAMAPTL3MBTL1 | |
| SCHEMBL8167586 | 0.75 | PTGER1 (0.59) | GAASGMS2PTGER1LMNAMAPT | |
| SCHEMBL9054578 | 0.74 | KDM4E (0.55) | GAASGMS2LMNAMAPTL3MBTL1 | |
| Bicarbonate SCHEMBL27963003 | 0.74 | HTR1A (0.61) | GAASGMS2PTGER1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085663-C | Aromatic amino ethers as analgesic agents | ZENECA LTD (GB) | 2002-05-29 | — | — | CN | disclosed |
| CN-1286254-A | Aromatic amino ethers as analgesic agents | ZENECA LTD (GB) | 2001-03-07 | — | — | CN | disclosed |
| CN-1154106-A | Aromatic amino ethers as analgesic agents | ZENECA LTD (GB) | 1997-07-09 | — | — | CN | disclosed |