Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.76 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20983505 | 0.89 | MRGPRX2 (0.82) | MRGPRX2OPRD1OPRM1OPRK1ADRB1 | |
| SCHEMBL29459625 | 0.87 | MRGPRX2 (1.00) | MRGPRX2OPRD1OPRM1OPRK1ADRB1 | |
| SCHEMBL5108263 | 0.87 | MRGPRX2 (1.00) | MRGPRX2OPRD1OPRM1OPRK1ADRB1 | |
| Hydrochloric Acid SCHEMBL8168636 | 0.86 | MRGPRX2 (0.98) | MRGPRX2OPRD1OPRM1OPRK1ADRB1 | |
| SCHEMBL29583693 | 0.82 | MRGPRX2 (1.00) | MRGPRX2OPRD1OPRM1OPRK1 | |
| SCHEMBL154048 | 0.82 | MRGPRX2 (1.00) | MRGPRX2OPRD1OPRM1OPRK1 | |
| SCHEMBL29449917 | 0.82 | MRGPRX2 (1.00) | MRGPRX2OPRD1OPRM1OPRK1 | |
| Methoxymethane SCHEMBL27466715 | 0.81 | MRGPRX2 (0.94) | MRGPRX2OPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL27754570 | 0.81 | MRGPRX2 (0.98) | MRGPRX2OPRD1OPRM1OPRK1 | |
| SCHEMBL24880 | 0.80 | OPRD1 (0.74) | MRGPRX2OPRD1OPRM1OPRK1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152880-C | Process for preparation of oxymorphone, oxycodone and derivatives | — | 2004-06-09 | — | — | CN | disclosed |
| CN-1272845-A | Process for preparation of oxymorphone, oxycodone and derivatives | PENICK CORP (US) | 2000-11-08 | — | — | CN | disclosed |