Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544982 | 0.81 | ESR1 (0.41) | — | |
| SCHEMBL2574068 | 0.79 | KEAP1 (0.63) | LMNATYRESRRGALDH1A1TDP1 | |
| SCHEMBL4814389 | 0.78 | TRPA1 (0.45) | ALDH1A1KMT2AKDM4EHPGDALOX15 | |
| SCHEMBL5366191 | 0.77 | KEAP1 (0.59) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL348623 | 0.76 | TSHR (0.52) | LMNATYRALDH1A1TDP1ADRA2A | |
| SCHEMBL12733320 | 0.75 | LMNA (0.73) | LMNATYRESRRGALDH1A1KMT2A | |
| SCHEMBL28020633 | 0.75 | NR4A2 (0.47) | LMNAESRRGNLRP3TDP1EPHX2 | |
| SCHEMBL875676 | 0.74 | BCL2 (0.54) | LMNAALDH1A1KMT2AKDM4ETDP1 | |
| SCHEMBL11011851 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4ETDP1HPGD | |
| SCHEMBL574142 | 0.74 | LMNA (0.51) | LMNAALDH1A1KMT2AHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184117-A | Novel alpha-aminoacetophenone photoinitiators | CIBA SC HOLDING AG (CH) | 1998-06-10 | — | — | CN | disclosed |