Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696347 | 0.78 | PRKDC (0.41) | CCNCCDK8PRKDC | |
| SCHEMBL1318411 | 0.72 | LMNA (0.42) | CCNCCDK8 | |
| SCHEMBL27728844 | 0.70 | ALDH1A1 (0.48) | PRKDC | |
| SCHEMBL5813899 | 0.69 | XDH (0.43) | — | |
| SCHEMBL7459787 | 0.68 | PRKDC (0.35) | PRKDC | |
| SCHEMBL5705105 | 0.68 | CYP3A4 (0.38) | PRKDC | |
| SCHEMBL5813585 | 0.67 | — | — | |
| SCHEMBL1381854 | 0.67 | PDE10A (0.40) | PRKDC | |
| SCHEMBL17057025 | 0.66 | DPP4 (0.41) | CCNCCDK8PRKDC | |
| SCHEMBL9173111 | 0.66 | PTGS2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675320-A | Process for synthesizing indiplon serving as sedative hypnotic medicine suitable for industrial production | INST PHARM & TOXICOLOGY AMMS | 2012-09-19 | — | — | CN | claimed |
| CN-1906197-A | Two-phase method for the synthesis of selected pyrazolopyrimidines | MALLINCKRODT INC (US) | 2007-01-31 | — | — | CN | claimed |
| CN-102174048-B | Novel polymorphic form beta of soporifics | INST RADIATION MED AMMS PLA | 2014-09-17 | — | — | CN | disclosed |
| CN-102180879-B | Polycrystalline type alpha acetic acid solvate of hypnotic | INST RADIATION MED AMMS PLA | 2013-05-01 | — | — | CN | disclosed |
| CN-102675320-A | Process for synthesizing indiplon serving as sedative hypnotic medicine suitable for industrial production | INST PHARM & TOXICOLOGY AMMS | 2012-09-19 | — | — | CN | disclosed |
| CN-101870700-B | Method for synthesizing Indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2012-05-23 | — | — | CN | disclosed |
| CN-102180879-A | Polycrystalline type alpha acetic acid solvate of hypnotic | INST RADIATION MED AMMS PLA | 2011-09-14 | — | — | CN | disclosed |
| CN-102174048-A | Novel polymorphic form beta of soporifics | INST RADIATION MED AMMS PLA | 2011-09-07 | — | — | CN | disclosed |
| CN-101591338-B | Method for synthesizing indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2011-07-20 | — | — | CN | disclosed |
| CN-101177427-B | Polymorphic form alpha and solvate of a hypnotic compound, process for preparing same and composition containing same | INST RADIATION MED AMMS PLA | 2011-07-20 | — | — | CN | disclosed |
| CN-101870700-A | Method for synthesizing Indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2010-10-27 | — | — | CN | disclosed |
| CN-101591338-A | The synthetic method of indene | UNIV PLA 3RD MILITARY MEDICAL (CN) | 2009-12-02 | — | — | CN | disclosed |
| CN-101177427-A | Polymorphic form alpha and solvate of a hypnotic compound, process for preparing same and composition containing same | RADIATION AND IRRADIATION MEDI (CN) | 2008-05-14 | — | — | CN | disclosed |
| CN-1331865-C | Polymorphs of n-methyl-n-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5- alpha ]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto | NEUROCRINE BIOSCIENCES INC (US) | 2007-08-15 | — | — | CN | disclosed |
| CN-1906197-A | Two-phase method for the synthesis of selected pyrazolopyrimidines | MALLINCKRODT INC (US) | 2007-01-31 | — | — | CN | disclosed |
| CN-1680376-A | Polymorphs of n-methyl-n-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5- alpha ]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto | NEUROCRINE BIOSCIENCES INC (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1198824-C | Polymorphic forms of N-methyl-N- (3- {3- [ 2-thienylcarbonyl ] -pyrazol- [1, 5-alpha ] -pyrimidin-7-yl } phenyl) acetamide | NEUROCRINE BIOSCIENCES INC (US) | 2005-04-27 | — | — | CN | disclosed |
| CN-1374866-A | Polymorphs of N-methyl-N- (3- { 3- [ 2-thienylcarbonyl ] -pyrazol- [1, 5-alpha ] -pyrimidin-7-yl } phenyl) acetamide and compositions containing same and related methods of preparation | NEUROCRINE BIOSCIENCES INC (US) | 2002-10-16 | — | — | CN | disclosed |