SCHEMBL27728844

SCHEMBL27728844

Nc1ccccc1-c1ccsc1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 2/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 2/20 0.37
PTPRC P08575 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
PPARG P37231 1/20 0.34
NCOA2 Q15596 1/20 0.34
NCOA1 Q15788 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
IDO1 P14902 2/20 0.33
TERT O14746 1/20 0.33
PRKDC P78527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696347 0.82 PRKDC (0.41) ALDH1A1L3MBTL1MEN1NPC1MAPT
SCHEMBL7459787 0.79 PRKDC (0.35) ALDH1A1HSD17B10MEN1NPC1MAPT
SCHEMBL5712471 0.77 MAOA (0.40) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL11156944 0.75 CA12 (0.40) ALDH1A1MEN1NPC1MAPTRAB9A
SCHEMBL967386 0.75 RORC (0.47) ALDH1A1MEN1NPC1MAPTRAB9A
SCHEMBL2461016 0.75 BCAT2 (0.47) ALDH1A1HSD17B10MEN1NPC1MAPT
SCHEMBL14398058 0.74 KDM4E (0.46) ALDH1A1L3MBTL1NPC1MAPTRAB9A
SCHEMBL13578971 0.74 APP (0.49) ALDH1A1L3MBTL1MEN1NPC1MAPT
SCHEMBL1695498 0.73
SCHEMBL2460904 0.73 ALDH1A1 (0.47) ALDH1A1L3MBTL1HSD17B10MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101176217-B Azaperylenes as organic semiconductors CIBA SC HOLDING AG 2013-07-17 CN disclosed
CN-101176217-A Azaperylenes as organic semiconductors CIBA SC HOLDING AG (CH) 2008-05-07 CN disclosed