Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511718 | 1.00 | SIGMAR1 (0.47) | SIGMAR1FAAHSMN1; SMN2HRH2S1PR5 | |
| SCHEMBL27493008 | 0.86 | MLNR (0.43) | SIGMAR1FAAHS1PR5 | |
| SCHEMBL27524925 | 0.83 | HIF1A (0.47) | SIGMAR1FAAHS1PR5 | |
| SCHEMBL28141724 | 0.80 | S1PR5 (0.41) | SIGMAR1S1PR5 | |
| SCHEMBL28023906 | 0.78 | MMP1 (0.46) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27532268 | 0.77 | SIGMAR1 (0.45) | SIGMAR1FAAHS1PR5ALDH1A1 | |
| SCHEMBL23540940 | 0.76 | SIGMAR1 (0.49) | SIGMAR1FAAHS1PR5 | |
| SCHEMBL28046102 | 0.76 | KDM4E (0.47) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL12520647 | 0.73 | LTA4H (0.63) | SIGMAR1SMN1; SMN2HRH2 | |
| SCHEMBL4287551 | 0.73 | LTA4H (0.63) | SIGMAR1SMN1; SMN2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152877-C | Piperazine derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1334812-A | Piperazine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-02-06 | — | — | CN | disclosed |