Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758223 | 0.86 | KMT2A (0.35) | MEN1KMT2ATDP1PDPK1PTGS2 | |
| SCHEMBL1017170 | 0.85 | EDNRB (0.37) | EDNRBEDNRAPLCG1CA2L3MBTL1 | |
| SCHEMBL28945097 | 0.81 | GSTO1 (0.44) | MEN1KMT2AL3MBTL1PTGES2GSTO1 | |
| SCHEMBL27807461 | 0.81 | CCR2 (0.35) | MEN1KMT2ATDP1GSTO1 | |
| SCHEMBL16656644 | 0.80 | EDNRB (0.36) | EDNRBEDNRAPLCG1PTGS2CA2 | |
| SCHEMBL27624382 | 0.77 | ADRA1D (0.42) | MEN1KMT2ACA2L3MBTL1PTGES2 | |
| SCHEMBL27690017 | 0.77 | CCR2 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL27624387 | 0.73 | KCNJ1 (0.39) | MEN1KMT2A | |
| SCHEMBL4157506 | 0.72 | LMNA (0.47) | EDNRBEDNRAMEN1KMT2ACA2 | |
| SCHEMBL7657078 | 0.72 | TDP1 (0.44) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231465-C | Biphenylsulfonyl cyanamides, method for the production thereof and use thereof as medicaments | AVENTIS PHARMACEUTIC DEUTSCHLA (DE) | 2005-12-14 | — | — | CN | disclosed |
| CN-1211370-C | Imidazole derivatives with biphenylsulfonyl substituents, process for their preparation and their use as pharmaceuticals or diagnostic agents | AVENTIS PHARMA GMBH (DE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1177827-C | Biphenylsulfonyl-substd. imidazole derivs., their preparation process, their use as drug or diagnostic agent and drug contg. them | ���ĵ�˹ҩ��¹�����˾ | 2004-12-01 | — | — | CN | disclosed |
| CN-1309645-A | Imidazole derivatives with biphenylsulfonyl substituents, process for their preparation and their use as pharmaceuticals or diagnostic agents | AVENTIS PHARMA GMBH (DE) | 2001-08-22 | — | — | CN | disclosed |
| CN-1309644-A | Biphenylsulfonyl-substituted imidazole derivatives, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2001-08-22 | — | — | CN | disclosed |
| CN-1289321-A | Biphenylsulfonyl cyanamides, method for the production thereof and their utilization as a medicament | AVENTIS PHARMACEUTIC DEUTSCHLA (DE) | 2001-03-28 | — | — | CN | disclosed |