Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067050 | 0.81 | PTGES (0.43) | FABP3FABP4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL20108650 | 0.79 | TYMP (0.42) | FABP3FABP4CYP1A2CYP2A6LMNA | |
| SCHEMBL9720735 | 0.77 | USP7 (0.34) | CYP2C9CYP1A2CYP2C19TDP1ALDH1A1 | |
| SCHEMBL31067193 | 0.75 | PBRM1 (0.44) | SMARCA2SMARCA4PBRM1KCNN4CYP2C9 | |
| Methane SCHEMBL27503142 | 0.75 | CYP2A6 (0.62) | CYP2A6PDK2ALDH1A1MAOBPTGS1 | |
| SCHEMBL9720758 | 0.73 | PDCD1 (0.41) | KCNN4CYP2C9CYP1A2CYP2C19PDK2 | |
| SCHEMBL2161599 | 0.73 | CYP2A6 (0.65) | CYP2A6PDK2ALDH1A1MAOBPTGS1 | |
| SCHEMBL533630 | 0.72 | PTGS2 (0.50) | PDK2ALDH1A1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL8974385 | 0.72 | CYP2A6 (0.50) | KCNN4CYP2C9CYP1A2CYP2C19TDP1 | |
| Chloromethane SCHEMBL29088511 | 0.71 | PTGS2 (0.50) | PDK2ALDH1A1PTPRCPTPN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437403-A | Treatment methods using triaryl methane compounds | ICAGEN INC (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-1193748-C | Gardos channel antagonists | ICAGEN INC (US) | 2005-03-23 | — | — | CN | disclosed |
| CN-1344158-A | Gardos channel antagonists | ICAGEN INC (US) | 2002-04-10 | — | — | CN | disclosed |