Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471083 | 0.95 | ITGB1 (0.39) | PTGS2ALDH1A1ESR1POLBHPGD | |
| SCHEMBL27489270 | 0.88 | PTGS2 (0.42) | PTGS2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL27488603 | 0.88 | PTGS2 (0.42) | PTGS2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL27522834 | 0.87 | ITGB1 (0.39) | PTGS2ALDH1A1IDO1TDO2RAB9A | |
| SCHEMBL27549351 | 0.83 | RAB9A (0.44) | PTGS2POLBHPGDRAB9ANPC1 | |
| SCHEMBL27487528 | 0.83 | SMN1; SMN2 (0.38) | ALDH1A1ESR1POLBHPGDIDO1 | |
| SCHEMBL27471545 | 0.82 | IDO1 (0.38) | ALDH1A1ESR1POLBHPGDIDO1 | |
| SCHEMBL4186885 | 0.81 | PTGS2 (0.61) | PTGS2 | |
| SCHEMBL27488605 | 0.81 | NPBWR1 (0.36) | ALDH1A1ESR1POLBHPGDIDO1 | |
| SCHEMBL27508687 | 0.81 | PLAT (0.35) | ALDH1A1ESR1POLBHPGDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |