Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471545 | 0.93 | IDO1 (0.38) | SMN1; SMN2ARIDO1TDO2THRB | |
| SCHEMBL27487888 | 0.91 | ALDH1A2 (0.35) | SMN1; SMN2ARIDO1TDO2GRIN1 | |
| SCHEMBL27472008 | 0.89 | RAB9A (0.42) | SMN1; SMN2ALDH1A1POLBHPGDNPSR1 | |
| SCHEMBL27488957 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2ARNR3C1ALDH1A1HPGD | |
| SCHEMBL27471083 | 0.88 | ITGB1 (0.39) | SMN1; SMN2IDO1TDO2GRIN1GRIN2B | |
| SCHEMBL4195928 | 0.86 | PTGS2 (0.46) | — | |
| SCHEMBL27471546 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2NR3C1ALDH1A1POLBHPGD | |
| SCHEMBL27488605 | 0.84 | NPBWR1 (0.36) | ARIDO1TDO2ALDH1A1POLB | |
| SCHEMBL27488239 | 0.83 | PTGS2 (0.38) | SMN1; SMN2IDO1TDO2ALDH1A1POLB | |
| SCHEMBL27555430 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2NR3C1ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |