Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470573 | 0.82 | MAPK14 (0.40) | PTGS2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27487529 | 0.80 | MAPT (0.40) | PTGS2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4183493 | 0.78 | PTGS2 (0.59) | PTGS1PTGS2 | |
| SCHEMBL27487523 | 0.77 | NPBWR1 (0.53) | PTGS1PTGS2ALDH1A1NPBWR1NPSR1 | |
| SCHEMBL27470076 | 0.76 | PTGS2 (0.71) | PTGS1PTGS2NPBWR1NPSR1 | |
| SCHEMBL15577465 | 0.73 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL27522828 | 0.72 | FYN (0.39) | MAPK14PRMT5WDR77 | |
| SCHEMBL27470080 | 0.69 | MAPT (0.38) | MAPK14MAPTLMNAMEN1KMT2A | |
| SCHEMBL27587261 | 0.68 | PTGS2 (0.47) | PTGS1PTGS2MAPK14MAPTKDM4E | |
| SCHEMBL14198825 | 0.67 | IDO1 (0.46) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |