SCHEMBL6566813

SCHEMBL6566813

CC(C)(c1ccccc1)c1cccc(OC(=O)CC[C@H](N)C(=O)O)c1C(C)(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.43
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566809 0.92 KIF11 (0.34) KIF11LTA4H
SCHEMBL1681408 0.85 KDM4E (0.45)
SCHEMBL6566814 0.85 RBP4 (0.35) KIF11LTA4H
SCHEMBL1681409 0.82 MEN1 (0.42)
SCHEMBL27488778 0.81 TDP1 (0.37) KIF11
SCHEMBL29601094 0.78 TDP1 (0.40)
SCHEMBL247099 0.78 TDP1 (0.40)
SCHEMBL247100 0.78 TDP1 (0.40)
SCHEMBL245087 0.74 ATM (0.37)
SCHEMBL27819527 0.74 ATM (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780409-B1 Low fogging rubbery polymer ELIOKEM SAS (FR) 2004-03-31 EP disclosed
EP-0780409-A2 Low fogging rubbery polymer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-06-25 EP disclosed