Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318078 | 1.00 | MMP1 (0.51) | MMP1MMP3KMT2ANOS3NOS1 | |
| SCHEMBL7029376 | 0.84 | MMP1 (0.51) | MMP1MMP3GAAACEMME | |
| SCHEMBL8022821 | 0.84 | MMP1 (0.51) | MMP1MMP3GAAACEMME | |
| SCHEMBL12668881 | 0.84 | NOS2 (0.46) | MMP1MMP3NOS3NOS1NOS2 | |
| SCHEMBL14942929 | 0.84 | NOS2 (0.46) | MMP1MMP3NOS3NOS1NOS2 | |
| SCHEMBL24711923 | 0.84 | NOS2 (0.46) | MMP1MMP3NOS3NOS1NOS2 | |
| SCHEMBL805199 | 0.84 | ALDH1A1 (0.56) | KMT2ANOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL4608578 | 0.84 | ALDH1A1 (0.56) | KMT2ANOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL4608581 | 0.84 | ALDH1A1 (0.56) | KMT2ANOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL26304810 | 0.84 | MMP1 (0.43) | MMP1MMP3KMT2AGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1220609-A | Growth hormone component and bone anti-resorptive agent in cyclic (coherence) treatment of osteoporosis | NOVO NORDISK AS (DK) | 1999-06-23 | — | — | CN | disclosed |
| CN-1211991-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-03-24 | — | — | CN | disclosed |